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Stage I and II pelvic radiation therapy Generally they have worse prognosis than endometrial cancers of a similar stage

A movement in the software development community to make the source code of applications available for other people to work on Although this will never become standard for commercial games, it is increasingly popular for tools and middleware

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How common is ovarian cancer It is the second most common gynecologic malignancy, but the leading cause of mortality among women who develop a gynecologic malignancy, and the fifth most common cause of cancer-related female deaths in the United States The lifetime risk of developing ovarian cancer is 14% (1 in 70) Symptoms of early-stage ovarian cancer are ill-defined and many women will not seek medical attention Often, the cancer is detected at its advanced stages when it has spread beyond the ovaries Epithelial origin; germ cell tumors; sex cord-stromal tumors; cancer metastatic to the ovary (usually from primary tumors of the breast, GI tract, or genital tract) Epithelial (~90% of all ovarian tumors)

OpenGL An open-source hardware-independent API for displaying graphics in a machine-independent fashion Its competition is DirectX for Windows Performance analyzer

What age group does EOC affect What is thought to be the underlying hypothesis in the development of EOC Predominantly postmenopausal women Median age is 62 years old It is not well understood, but one hypothesis is that repetitive ovulation where disruption and repair of the ovarian epithelium may allow opportunity for genetic mutation and malignant transformation

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Persistent world An online game that simulates a world that continues to exist and change even while a player is logged off MMORPGs are persistent worlds, but a persistent world need not be massively-multiplayer, nor need it be a role-playing game

Family history of breast cancer or EOC; history of breast cancer; advanced age; obesity/high fat diet; infertility; nulliparity; talc; endometriosis OCPs; tubal ligation; breastfeeding (history of); pregnancy; multiparity 90% are sporadic; 10% are genetic predisposition The onset of ovarian cancer occurs 10 years earlier in hereditary syndromes 1 Breast and ovarian cancer (BOC): associated with BRCA-1 mutation (autosomal dominant), more susceptibility to BOC, higher frequencies in Ashkenazi Jews 2 Lynch II Syndrome (hereditary nonpolyposis colon cancer HNPCC): colorectal cancer is hallmark, also commonly found are endometrial, urogenital, and other GI primaries 3 Site-specific ovarian cancer: strong genetic link, autosomal dominant, usually two or more first-degree relatives have the disease 1 Prophylactic genetic screening 2 CA-125 and transvaginal ultrasound every 6 12 months beginning between ages 25 and 35 years Prophylactic oophorectomy who have completed childbearing or by age 35 Endometriosis (25%) Serous 75 80% Mucinous 10% Endometrioid 10% Clear cell <1% Transitional cell <1% Undifferentiated <10%

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The fundamental unit of graphical data displayed by a 3-D graphics engine A polygon is a region in 3-D space described by three or four points called vertices The points make up a triangle or quadrilateral (usually abbreviated quad ); polygon is a generic term for either Three-dimensional models are built up out of hundreds or thousands of polygons to create a surface Some game engines are designed to work with triangles, others with quads Most modeling tools are capable of producing either

What factors are protective against development of EOC What percent of EOC develops sporadically What percent are because of genetic predisposition What is one feature that distinguishes hereditary ovarian cancer from a somatic cause With what hereditary syndromes has ovarian cancer been associated Describe them

Polygon Polygons per second A measure of the speed of 3-D acceleration hardware The more polygons an accelerator can display per second, the more detailed a scene it can display before having to reduce the frame rate Porting

What other preventative surgical procedure is recommended for women with a presumed hereditary ovarian cancer syndrome With what other gynecologic disease is ovarian cancer associated What are the subtypes of EOC and how common is each type

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